In a medium mixing bowl, whisk together the ketchup, brown sugar, and water until the sugar begins to dissolve. This creates your sauce foundation and ensures even sweetness distribution throughout.

Pour in the red wine vinegar, Worcestershire sauce, and prepared mustard. Whisk vigorously for about 30 seconds until everything is completely incorporated and the mixture looks uniform in color and texture.

Add the black pepper, onion powder, garlic powder, cayenne pepper, and salt. Whisk thoroughly to distribute all the seasonings evenly, making sure there are no clumps of spices.

Dip a clean spoon and taste your creation. Adjust seasoning as needed - add more vinegar for tang, brown sugar for sweetness, or salt and pepper to taste.

Transfer your homemade BBQ sauce to a jar or airtight container. Let it sit in the refrigerator for at least 2 hours before using to allow all the flavors to marry and meld. Overnight is even better.

Before using, stir or shake the sauce well to recombine any separated ingredients.